Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/92365
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Applied Biology and Chemical Technology | en_US |
dc.creator | Yu, X | en_US |
dc.creator | Yao, ZP | en_US |
dc.date.accessioned | 2022-03-24T08:14:17Z | - |
dc.date.available | 2022-03-24T08:14:17Z | - |
dc.identifier.issn | 0003-2670 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/92365 | - |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | © 2017 Elsevier B.V. All rights reserved. | en_US |
dc.rights | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
dc.rights | The following publication Yu, X., & Yao, Z. P. (2017). Chiral recognition and determination of enantiomeric excess by mass spectrometry: A review. Analytica Chimica Acta, 968, 1-20 is available at https://dx.doi.org/10.1016/j.aca.2017.03.021 | en_US |
dc.subject | Chiral recognition | en_US |
dc.subject | Enantiomeric excess (ee) | en_US |
dc.subject | Ion mobility | en_US |
dc.subject | Mass spectrometry | en_US |
dc.title | Chiral recognition and determination of enantiomeric excess by mass spectrometry : a review | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 1 | en_US |
dc.identifier.epage | 20 | en_US |
dc.identifier.volume | 968 | en_US |
dc.identifier.doi | 10.1016/j.aca.2017.03.021 | en_US |
dcterms.abstract | Chiral analysis is of great importance to fundamental and applied research in chemical, biological and pharmaceutical sciences. Due to the superiority of mass spectrometry (MS) over other analytical methods in terms of speed, specificity and sensitivity, chiral analysis by MS has attracted much interest in recent years. Chiral analysis by MS typically involves introduction of a chiral selector to form diastereomers with analyte enantiomers, and comparison of the behaviors of diastereomers in MS. Chiral differentiation can be achieved by comparing the relative abundances of diastereomers, the thermodynamic or kinetic constants of ion-molecule reactions of diastereomers in the gas phase, the dissociation of diastereomers in MS/MS, or the mobility of diastereomers in ion mobility mass spectrometry. In this review, chiral recognition and determination of enantiomeric excess by these chiral MS methods were summarized, and the prospects of chiral analysis by MS were discussed. | en_US |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Analytica chimica acta, 22 May 2017, v. 968, p. 1-20 | en_US |
dcterms.isPartOf | Analytica chimica acta | en_US |
dcterms.issued | 2017-05 | - |
dc.identifier.scopus | 2-s2.0-85016223154 | - |
dc.identifier.pmid | 28395770 | - |
dc.description.validate | 202203 bcfc | en_US |
dc.description.oa | Accepted Manuscript | en_US |
dc.identifier.FolderNumber | RGC-B1-121, ABCT-0647 | en_US |
dc.description.fundingSource | RGC | en_US |
dc.description.fundingSource | Others | en_US |
dc.description.fundingText | State Key Laboratory of Chirosciences; The Hong Kong Polytechnic University | en_US |
dc.description.pubStatus | Published | en_US |
dc.identifier.OPUS | 6978801 | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Yu_Chiral_Recognition_Determination.pdf | Pre-Published version | 2.31 MB | Adobe PDF | View/Open |
Page views
59
Last Week
0
0
Last month
Citations as of May 12, 2024
Downloads
155
Citations as of May 12, 2024
SCOPUSTM
Citations
86
Citations as of May 16, 2024
WEB OF SCIENCETM
Citations
78
Citations as of May 16, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.