Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/88856
DC Field | Value | Language |
---|---|---|
dc.contributor | Institute of Textiles and Clothing | en_US |
dc.contributor | Department of Health Technology and Informatics | en_US |
dc.creator | Zhang, Z | en_US |
dc.creator | Li, J | en_US |
dc.creator | Ma, L | en_US |
dc.creator | Yang, X | en_US |
dc.creator | Fei, B | en_US |
dc.creator | Leung, PHM | en_US |
dc.creator | Tao, X | en_US |
dc.date.accessioned | 2020-12-22T06:03:31Z | - |
dc.date.available | 2020-12-22T06:03:31Z | - |
dc.identifier.issn | 2073-4360 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/88856 | - |
dc.language.iso | en | en_US |
dc.publisher | Molecular Diversity Preservation International (MDPI) | en_US |
dc.rights | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | en_US |
dc.rights | The following publication Zhang, Z., Li, J., Ma, L., Yang, X., Fei, B., Leung, P. H. M., & Tao, X. (2020). Mechanistic study of synergistic antimicrobial effects between poly (3-hydroxybutyrate) oligomer and polyethylene glycol. Polymers, 12(11), 1-12 is available at https://dx.doi.org/10.3390/polym12112735 | en_US |
dc.subject | Antimicrobial agent | en_US |
dc.subject | Oligomer | en_US |
dc.subject | Poly (3-Hydroxybutyric acid) | en_US |
dc.subject | Polyethylene glycol | en_US |
dc.subject | Synergistic antimicrobial effect | en_US |
dc.title | Mechanistic study of synergistic antimicrobial effects between poly (3-hydroxybutyrate) oligomer and polyethylene glycol | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 1 | en_US |
dc.identifier.epage | 12 | en_US |
dc.identifier.volume | 12 | en_US |
dc.identifier.issue | 11 | en_US |
dc.identifier.doi | 10.3390/polym12112735 | en_US |
dcterms.abstract | Extended from our previous finding that poly (3-hydroxybutyrate) (PHB) oligomer is an effective antimicrobial agent against gram-positive bacteria, gram-negative bacteria, fungi and multi-drug resistant bacteria, this work investigates the effect of polyethylene glycol (PEG) on the antimicrobial effect of PHB oligomer. To investigate and explain this promoting phenomenon, three hypothetic mechanisms were proposed, that is, generation of new antimicrobial components, degradation of PHB macromolecules and dissolution/dispersion of PHB oligomer by PEG. With a series of systematic experiments and characterizations of high-performance liquid chromatography–mass spectrometry (HPLC-MS), it was deducted that PEG promotes the antimicrobial effect of PHB oligomer synergistically through dissolution/dispersion, owing to its amphipathy, which improves the hydrophilicity of PHB oligomer. | en_US |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Polymers, Nov. 2020, v. 12, no. 11, 2735, p. 1-12 | en_US |
dcterms.isPartOf | Polymers | en_US |
dcterms.issued | 2020-11 | - |
dc.identifier.scopus | 2-s2.0-85096575440 | - |
dc.identifier.artn | 2735 | en_US |
dc.description.validate | 202012 bcrc | en_US |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | a0520-n05 | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
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polymers-12-02735-v2.pdf | 5.43 MB | Adobe PDF | View/Open |
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