Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/88733
Title: | Biochemical and histopathological profiling of Wistar rat treated with Brassica napus as a supplementary feed | Authors: | Hasan, KMM Tamanna, N Haque, MA |
Issue Date: | Mar-2018 | Source: | Food science and human wellness, Mar. 2018, v. 7, no. 1, p. 77-82 | Abstract: | Metabolic changes together with cardiovascular and hepatic factors are related to the development of diseases like myocardial lipidosis, heart disease, and profound toxicity. The aim of this animal study is to determine the effects of high erucic acid containing rapeseed oil (Brassica napus L.) varieties on liver, kidney and heart muscles in Wistar rats. Male Wistar rats were divided into three groups where each group containing four rats. Group A was considered as control diet group, while Group B rapeseed wild oil group and Group C rapeseed hybrid oil group were considered as experimental diet groups. The levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT),alkaline phosphatase(ALP), creatine kinase-MB (CK-MB) and creatinine of two experimental groups were significantly elevated while compared to the control groups (p < 0.05-0.001). Nevertheless, an increment in weight retardation (p < 0.05) was also observed in rapeseed hybrid oil treated groups. No significant weight retardation found in other two groups (p > 0.05). Noticeable tissue injury observed in this study is a sign of the relative toxicity of erucic acid containing rapeseed oil to mammalian species. The use of Brassica napus as a supplementary feed ingredient should be, therefore, thoroughly considered (C) 2018 Society information. Production and hosting by Elsevier B.V. | Keywords: | Rapeseed oil Rattus norvegicus Serum enzymes Erucic acid Tissue profiling |
Publisher: | Elsevier BV | Journal: | Food science and human wellness | EISSN: | 2213-4530 | DOI: | 10.1016/j.fshw.2017.12.002 | Rights: | © 2018 “Society information”. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article underthe CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). The following publication Hasan, K. M. M., Tamanna, N , & Haque, M. A. (2018). Biochemical and histopathological profiling of Wistar rat treated with Brassica napus as a supplementary feed. Food Science and Human Wellness, 7(1), 77-82 is available at https://dx.doi.org/10.1016/j.fshw.2017.12.002 |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Hasan_Biochemical_Histopathological_Profiling.pdf | 1.46 MB | Adobe PDF | View/Open |
Page views
47
Last Week
2
2
Last month
Citations as of Apr 28, 2024
Downloads
34
Citations as of Apr 28, 2024
SCOPUSTM
Citations
88
Citations as of Apr 26, 2024
WEB OF SCIENCETM
Citations
67
Citations as of May 2, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.