Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/88715
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Biomedical Engineering | - |
dc.creator | Wong, TW | - |
dc.creator | Kan, CD | - |
dc.creator | Chiu, WT | - |
dc.creator | Fok, KL | - |
dc.creator | Ruan, YC | - |
dc.creator | Jiang, XH | - |
dc.creator | Chen, JJ | - |
dc.creator | Kao, CC | - |
dc.creator | Chen, IY | - |
dc.creator | Lin, HC | - |
dc.creator | Chou, CH | - |
dc.creator | Lin, CW | - |
dc.creator | Yu, CK | - |
dc.creator | Tsao, S | - |
dc.creator | Lee, YP | - |
dc.creator | Chan, HC | - |
dc.creator | Wang, JN | - |
dc.date.accessioned | 2020-12-22T01:07:15Z | - |
dc.date.available | 2020-12-22T01:07:15Z | - |
dc.identifier.uri | http://hdl.handle.net/10397/88715 | - |
dc.language.iso | en | en_US |
dc.publisher | Molecular Diversity Preservation International (MDPI) | en_US |
dc.rights | © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | en_US |
dc.rights | The following publication Wong, T.-W.; Kan, C.-D.; Chiu, W.-T.; Fok, K.L.; Ruan, Y.C.; Jiang, X.; Chen, J.; Kao, C.-C.; Chen, I.-Y.; Lin, H.-C.; Chou, C.-H.; Lin, C.-W.; Yu, C.-K.; Tsao, S.; Lee, Y.-P.; Chan, H.C.; Wang, J.-N. Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children. J. Clin. Med. 2019, 8, 1028 is available at https://dx.doi.org/10.3390/jcm8071028 | en_US |
dc.subject | Congenital heart disease | en_US |
dc.subject | Cardiac surgery | en_US |
dc.subject | Open heart | en_US |
dc.subject | Progenitor cells | en_US |
dc.subject | Regeneration | en_US |
dc.subject | Stem cells | en_US |
dc.title | Progenitor cells derived from drain waste product of open-heart surgery in children | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 1 | - |
dc.identifier.epage | 22 | - |
dc.identifier.volume | 8 | - |
dc.identifier.issue | 7 | - |
dc.identifier.doi | 10.3390/jcm8071028 | - |
dcterms.abstract | Human cardiac progenitor cells isolated from the same host may have advantages over other sources of stem cells. The aim of this study is to establish a new source of human progenitor cells collected from a waste product, pericardiac effusion fluid, after open-heart surgery in children with congenital heart diseases. The fluid was collected every 24 h for 2 days after surgery in 37 children. Mononuclear cells were isolated and expanded in vitro. These pericardial effusion-derived progenitor cells (PEPCs) exhibiting cardiogenic lineage markers, were highly proliferative and enhanced angiogenesis in vitro. Three weeks after stem cell transplantation into the ischemic heart in mice, cardiac ejection fraction was improved significantly without detectable progenitor cells. Gene expression profiles of the repaired hearts revealed activation of several known repair mechanisms including paracrine effects, cell migration, and angiogenesis. These progenitor cells may have the potential for heart regeneration. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Journal of clinical medicine, July 2019, , v. 8, no. 7, 1028, p. 1-22 | - |
dcterms.isPartOf | Journal of clinical medicine | - |
dcterms.issued | 2019-07 | - |
dc.identifier.isi | WOS:000479003300113 | - |
dc.identifier.pmid | 31336927 | - |
dc.identifier.eissn | 2077-0383 | - |
dc.identifier.artn | 1028 | - |
dc.description.validate | 202012 bcrc | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_Scopus/WOS | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Wong_Progenitor_Cells_Derived.pdf | 4.58 MB | Adobe PDF | View/Open |
Page views
58
Last Week
0
0
Last month
Citations as of May 12, 2024
Downloads
15
Citations as of May 12, 2024
SCOPUSTM
Citations
1
Citations as of May 16, 2024
WEB OF SCIENCETM
Citations
1
Last Week
0
0
Last month
Citations as of May 16, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.