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Title: A small-sized benzothiazole–indolium fluorescentprobe: the study of interaction specificitytargeting c-MYC promoter G-quadruplexstructures and live cell imaging
Authors: Zheng, BX
She, MT
Long, W
Xu, YY
Zhang, YH
Huang, XH
Liu, W
Hou, JQ
Lu, YJ
Issue Date: 2020
Source: Chemical communications, 2020, p. 1-4
Abstract: A small-sized c-MYC promoter G-quadruplex selective fluorescentBZT-Indolium binding ligand was demonstrated for the first time as ahighly target-specific and photostable probe forin vitrostaining andlive cell imaging and it was found to beable to inhibit the amplificationof the c-MYC G-rich sequence (G-quadruplex) and down-regulateoncogene c-MYC expression inhuman cancer cells (HeLa)
Publisher: Royal Society of Chemistry
Journal: Chemical communications 
ISSN: 1359-7345
EISSN: 1364-548X
DOI: 10.1039/d0cc06525k
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