Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/8828
Title: Silk fibroin-based nanoparticles for drug delivery
Authors: Zhao, Z
Li, Y 
Xie, MB
Keywords: Drug delivery
Nanoparticles
Preparation methods
Silk fibroin
Issue Date: 2015
Publisher: MDPI AG
Source: International journal of molecular sciences, 2015, v. 16, no. 3, p. 4880-4903 How to cite?
Journal: International Journal of Molecular Sciences 
Abstract: Silk fibroin (SF) is a protein-based biomacromolecule with excellent biocompatibility, biodegradability and low immunogenicity. The development of SF-based nanoparticles for drug delivery have received considerable attention due to high binding capacity for various drugs, controlled drug release properties and mild preparation conditions. By adjusting the particle size, the chemical structure and properties, the modified or recombinant SF-based nanoparticles can be designed to improve the therapeutic efficiency of drugs encapsulated into these nanoparticles. Therefore, they can be used to deliver small molecule drugs (e.g., anti-cancer drugs), protein and growth factor drugs, gene drugs, etc. This paper reviews recent progress on SF-based nanoparticles, including chemical structure, properties, and preparation methods. In addition, the applications of SF-based nanoparticles as carriers for therapeutic drugs are also reviewed.
URI: http://hdl.handle.net/10397/8828
ISSN: 1661-6596
DOI: 10.3390/ijms16034880
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

19
Last Week
1
Last month
0
Citations as of Jan 22, 2017

WEB OF SCIENCETM
Citations

16
Last Week
1
Last month
1
Citations as of Jan 18, 2017

Page view(s)

18
Last Week
0
Last month
Checked on Jan 22, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.