Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/87854
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Title: Fluorescent materials with aggregation-induced emission characteristics for array-based sensing assay
Authors: Zhao, EG
Lai, PX 
Xu, YJ
Zhang, G
Chen, SJ
Issue Date: Apr-2020
Source: Frontiers in chemistry, Apr. 2020, v. 8, 288, p. 1-14
Abstract: Array-based sensing is a powerful tool for identifying analytes in complex environments with unknown interferences. In array-based sensing, the sensors, which transduce binding details to signal outputs, are of crucial importance for identifying analytes. Aggregation-induced emission luminogens (AIEgens) enjoy the advantages of easy synthesis and high sensitivity, which enable them to facilely form a sensor pool through structural modifications and sensitively reflect the subtle changes associated with binding events. All these features make AIEgens excellent candidates for array-based sensing, and attempts have been made by several research groups to explore their potentials in array-based sensing. In this review, we introduce the recent progresses of employing AIEgens as sensors in sensing assays and in building up sensor arrays for identification of varied biological analytes, including biomolecules and bacteria. Examples are selected to illustrate the working mechanism, probe design and selection, capability of the sensor array, and implications of these sensing methods.
Keywords: Aggregation-induced emission
Array-based sensing
Biological sensing
Bacteria identification
Sensor array
Publisher: Frontiers Media SA
Journal: Frontiers in chemistry 
EISSN: 2296-2646
DOI: 10.3389/fchem.2020.00288
Rights: © 2020 Zhao, Lai, Xu, Zhang and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)(https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
The following publication Zhao E, Lai P, Xu Y, Zhang G and Chen S (2020) Fluorescent Materials With Aggregation-Induced Emission Characteristics for Array-Based Sensing Assay. Front. Chem. 8:288 is available at https://dx.doi.org/10.3389/fchem.2020.00288
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