Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81615
Title: Data on corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a data independent quantification approach
Authors: Kang, BS 
Lam, TC 
Cheung, JKW 
Li, KK 
Kee, CS 
Keywords: Cornea
Corneal proteome
Myopia
Issue Date: 2019
Publisher: Elsevier
Source: Data in brief, 2019, v. 26, 104478 How to cite?
Journal: BMC pediatrics 
Abstract: Myopia is an abnormal refractive status, explained by an excessive ocular lengthening mostly in posterior segments. Although growing evidence of anterior segments, specifically altered corneal geometries with biomechanical properties in myopes have been reported, the mechanism behind is poorly understood. We hereby prepared experimentally induced highly myopic chicks to investigate the molecular basis of corneal remodeling by applying a novel proteomic approach integrated with information dependent acquisition (IDA) and data independent quantification (SWATH-MS) analysis. As a result, differentially expressed protein biomarkers that might be involved in structural changes were screened based on the first of its kind unique chicken corneal proteome. All generated raw data from IDA and SWATH-MS are accessible at Peptide Atlas public repository (http://www.peptideatlas.org/PASS/PASS01410) for general release.
URI: http://hdl.handle.net/10397/81615
ISSN: 2352-3409
DOI: 10.1016/j.dib.2019.104478
Rights: © 2019 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
The following publication Kang, B. S., Lam, T. C., Cheung, J. K. W., Li, K. K., & Kee, C. S. (2019). Data on corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a data independent quantification approach. Data in brief, 26, 104478 is available at https://doi.org/10.1016/j.dib.2019.104478
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