Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81088
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dc.contributor.authorChen, PMen_US
dc.contributor.authorKwong, PWHen_US
dc.contributor.authorLai, CKYen_US
dc.contributor.authorNg, SSMen_US
dc.date.accessioned2019-07-29T03:17:50Z-
dc.date.available2019-07-29T03:17:50Z-
dc.date.issued2019-
dc.identifier.citationPLoS one, 23 May 2019, v. 14, no. 5, e0216357, p. 1-21en_US
dc.identifier.urihttp://hdl.handle.net/10397/81088-
dc.description.abstractBackground and objectives Bilateral upper limb training (BULT) and unilateral upper limb training (UULT) are two effective strategies for the recovery of upper limb motor function after stroke. This meta-analysis aimed to compare the improvements in motor impairment and functional performances of people with stroke after BULT and UULT.en_US
dc.description.abstractResearch design and methods This systematic review and meta-analysis identified 21 randomized controlled trials (RCTs) met the eligibility criteria from CINAHL, Medline, Embase, Cochrane Library and PubMed. The outcome measures were the Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Wolf Motor Function Test (WMFT), Action Research Arm Test (ARAT) and Box and Block Test (BBT), which are validated measures of upper limb function.en_US
dc.description.abstractResults Twenty-one studies involving 842 subjects with stroke were included. Compared with UULT, BULT yielded a significantly greater mean difference (MD) in the FMA-UE (MD = 2.21, 95% Confidence Interval (CI), 0.12 to 4.30, p = 0.04; l(2) = 86%, p<0.001). However, a comparison of BULT and UULT yielded insignificant mean difference (MD) in terms of the time required to complete the WMFT (MD = 0.44; 95%CI, -2.22 to 3.10, p = 0.75; l(2) = 55%, p = 0.06) and standard mean difference (SMD) in terms of the functional ability scores on the WMFT, ARAT and BBT (SMD = 0.25; 95%CI, -0.02 to 0.52, p = 0.07; l(2) = 54%, p = 0.02).en_US
dc.description.abstractDiscussion and implications Compared to UULT, BULT yielded superior improvements in the improving motor impairment of people with stroke, as measured by the FMA-UE. However, these strategies did not yield significant differences in terms of the functional performance of people with stroke, as measured by the WMFT, ARAT and BBT. More comparative studies of the effects of BULT and UULT are needed to increase the reliability of these conclusions.en_US
dc.description.sponsorshipSchool of Nursingen_US
dc.language.isoenen_US
dc.publisherPublic Library of Scienceen_US
dc.relation.ispartofPLoS oneen_US
dc.rightsCopyright: © 2019 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.rightsThe following publication Chen P-m, Kwong PWH, Lai CKY, Ng SSM (2019) Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis. PLoS ONE 14(5): e0216357, 21 pages is available at https://dx.doi.org/10.1371/journal.pone.0216357en_US
dc.titleComparison of bilateral and unilateral upper limb training in people with stroke : a systematic review and meta-analysisen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage1-
dc.identifier.epage21-
dc.identifier.volume14-
dc.identifier.issue5-
dc.identifier.doi10.1371/journal.pone.0216357-
dc.identifier.isiWOS:000468775700014-
dc.identifier.pmid31120910-
dc.identifier.eissn1932-6203-
dc.identifier.artne0216357-
dc.description.validate201907 bcrc-
dc.description.oapublished_final-
Appears in Collections:Journal/Magazine Article
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