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Title: Exogenous neural stem cell transplantation for cerebral ischemia
Authors: Liao, LY
Lau, BWM 
Sanchez-Vidana, DI 
Gao, Q 
Keywords: Nerve regeneration
Stem cell therapy
Neural stem cells
Cell transplantation
Ischemic stroke
Cerebral ischemia
Functional recovery
Neural regeneration
Issue Date: 2019
Publisher: Medknow Publications and Media Pvt Ltd
Source: Neural regeneration research, July 2019, v. 14, no. 7, PMID 30804235, p. 1129-1137 How to cite?
Journal: Neural regeneration research 
Abstract: Cerebral ischemic injury is the main manifestation of stroke, and its incidence in stroke patients is 70-80%. Although ischemic stroke can be treated with tissue-type plasminogen activator, its time window of effectiveness is narrow. Therefore, the incidence of paralysis, hypoesthesia, aphasia, dysphagia, and cognitive impairment caused by cerebral ischemia is high. Nerve tissue regeneration can promote the recovery of the aforementioned dysfunction. Neural stem cells can participate in the reconstruction of the damaged nervous system and promote the recovery of nervous function during self-repair of damaged brain tissue. Neural stem cell transplantation for ischemic stroke has been a hot topic for more than 10 years. This review discusses the treatment of ischemic stroke with neural stem cells, as well as the mechanisms of their involvement in stroke treatment.
ISSN: 1673-5374
DOI: 10.4103/1673-5374.251188
Rights: This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-Non-Commercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
The following publication Liao LY, Lau BW, Sánchez-Vidaña DI, Gao Q. Exogenous neural stem cell transplantation for cerebral ischemia. Neural Regen Res 2019;14:1129-1137 is available at
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