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Title: An East meets West approach to the understanding of emotion dysregulation in depression : from perspective to scientific evidence
Authors: Ye, JJ 
Cai, SH
Cheung, WM
Tsang, HWH 
Keywords: Traditional Chinese medicine
East meets West
Neurophysiological pathway
Issue Date: 2019
Publisher: Frontiers Research Foundation
Source: Frontiers in psychology, 28 Mar. 2019, v. 10, 574, p. 1-12 How to cite?
Journal: Frontiers in psychology 
Abstract: Depression, an emotion regulation disorder, is a prevalent mental illness in the world. Meanwhile, traditional Chinese medicine (TCM) has been increasingly regarded as a promising and effective alternative therapy approach for patients with depression. Despite many years of research on depression, the current understanding of the pathological mechanism of depression based on TCM theories is still in its infancy. Due to the lack of scientific evidence in the past, TCM is not fully recognized by researchers around the world. This review firstly summarizes the pathogenesis and etiology of depression in terms of both Eastern and Western medical systems. Secondly, it adopts an integrated Eastern and Western approach to propose some plausible neurophysiological pathways linking the liver, spleen, and heart functions explicated in TCM theory. The aim of this theoretical review is to bridge the knowledge gap between Eastern and Western medicine, which may better explain the pathology of depression.
EISSN: 1664-1078
DOI: 10.3389/fpsyg.2019.00574
Rights: Copyright © 2019 Ye, Cai, Cheung and Tsang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) ( The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyrigh owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
The following publication Ye J, Cai S, Cheung WM and Tsang HWH (2019) An East Meets West Approach to the Understanding of Emotion Dysregulation in Depression: From Perspective to Scientific Evidence. Front. Psychol. 10:574, 12 pages is available at
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