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Title: Ultrafast polarization bio-imaging based on coherent detection and time-stretch techniques
Authors: Song, L
Feng, YH
Guo, XJ
Shen, YC
Wu, DX
Wu, ZH
Zhou, CR
Zhu, LY
Gao, SC
Liu, WP
Zhang, XM 
Li, ZH
Issue Date: 2018
Publisher: Optical Society of America
Source: Biomedical optics express, 1 Dec. 2018, v. 9, no. 12, p. 6556-6568 How to cite?
Journal: Biomedical optics express 
Abstract: Optical polarization imaging has played an important role in many biological and biomedical applications, as it provides a label-free and non-invasive detection scheme to reveal the polarization information of optical rotation, birefringence, and photoelasticity distribution inherent in biological samples. However, the imaging speeds of the previously demonstrated polarization imaging techniques were often limited by the slow frame rates of the arrayed imaging detectors, which usually run at frame rates of several hundred hertz. By combining the optical coherent detection of orthogonal polarizations and the optical time-stretch imaging technique, we achieved ultrafast polarization bio-imaging at an extremely fast record line scanning rate up to 100 MHz without averaging. We experimentally demonstrated the superior performance of our method by imaging three slices of different kinds of biological samples with the retrieved Jones matrix and polarization-sensitive information including birefringence and diattenuation. The proposed system in this paper may find potential applications for ultrafast polarization dynamics in living samples or some other advanced biomedical research.
EISSN: 2156-7085
DOI: 10.1364/BOE.9.006556
Rights: © 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement (
© 2018 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
Journal © 2018
The following publication Song, L., Feng, Y. H., Guo, X. J., Shen, Y. C., Wu, D. X., . . . Wu, Z. H.Li, Z. H. (2018). Ultrafast polarization bio-imaging based on coherent detection and time-stretch techniques. Biomedical Optics Express, 9(12), 6556-6568 is available at
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