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http://hdl.handle.net/10397/80358
Title: | Long non-coding RNAs in obesity-induced cancer | Authors: | Yau, MYC Xu, L Huang, CL Wong, CM |
Issue Date: | 28-Aug-2018 | Source: | Non-coding RNA, 2018, v. 4, no. 3, 19, p. 1-17 | Abstract: | Many mechanisms of obesity-induced cancers have been proposed. However, it remains unclear whether or not long non-coding RNAs (lncRNAs) play any role in obesity-induced cancers. In this article, we briefly discuss the generally accepted hypotheses explaining the mechanisms of obesity-induced cancers, summarize the latest evidence for the expression of a number of well-known cancer-associated lncRNAs in obese subjects, and propose the potential contribution of lncRNAs to obesity-induced cancers. We hope this review can serve as an inspiration to scientists to further explore the regulatory roles of lncRNAs in the development of obesity-induced cancers. Those findings will be fundamental in the development of effective therapeutics or interventions to combat this life-threatening adverse effect of obesity. | Keywords: | ANRIL Cancer H19 HOTAIR LncRNA Obesity |
Publisher: | MDPI AG | Journal: | Non-coding RNA | EISSN: | 2311-553X | DOI: | 10.3390/ncrna4030019 | Rights: | ©2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open accessarticle distributed under the terms and conditions of the Creative Commons Attribution(CC BY) license (http://creativecommons.org/licenses/by/4.0/) The following publication Yau, M.Y.-C.; Xu, L.; Huang, C.-L.; Wong, C.-M. Long Non-Coding RNAs in Obesity-Induced Cancer. Non-Coding RNA 2018, 4, 19, 1-17 is available at https://doi.org/10.3390/ncrna4030019 |
Appears in Collections: | Journal/Magazine Article |
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