Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/80358
Title: Long non-coding RNAs in obesity-induced cancer
Authors: Yau, MYC
Xu, L
Huang, CL 
Wong, CM 
Keywords: ANRIL
Cancer
H19
HOTAIR
LncRNA
Obesity
Issue Date: 2018
Publisher: MDPI AG
Source: Non-coding RNA, 2018, v. 4, no. 3, 19 How to cite?
Journal: Non-coding RNA 
Abstract: Many mechanisms of obesity-induced cancers have been proposed. However, it remains unclear whether or not long non-coding RNAs (lncRNAs) play any role in obesity-induced cancers. In this article, we briefly discuss the generally accepted hypotheses explaining the mechanisms of obesity-induced cancers, summarize the latest evidence for the expression of a number of well-known cancer-associated lncRNAs in obese subjects, and propose the potential contribution of lncRNAs to obesity-induced cancers. We hope this review can serve as an inspiration to scientists to further explore the regulatory roles of lncRNAs in the development of obesity-induced cancers. Those findings will be fundamental in the development of effective therapeutics or interventions to combat this life-threatening adverse effect of obesity.
URI: http://hdl.handle.net/10397/80358
EISSN: 2311-553X
DOI: 10.3390/ncrna4030019
Rights: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
The following publication: Yau, M.Y.-C.; Xu, L.; Huang, C.-L.; Wong, C.-M. Long Non-Coding RNAs in Obesity-Induced Cancer. Non-Coding RNA 2018, 4, 19 is available at https://doi.org/10.3390/ncrna4030019
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