Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/79931
Title: Developing transmission line equations of oxygen transport for predicting oxygen distribution in the arterial system
Authors: Yan, F 
Jiang, WT
Xu, Z 
Wang, QY
Fan, YB
Zhang, M 
Issue Date: 2018
Publisher: Nature Publishing Group
Source: Scientific reports, 29 Mar. 2018, v. 8, 5369 How to cite?
Journal: Scientific reports 
Abstract: The oxygen content in the arterial system plays a significant role in determining the physiological status of a human body. Understanding the oxygen concentration distribution in the arterial system is beneficial for the prevention and intervention of vascular disease. However, the oxygen concentration in the arteries could not be noninvasively monitored in clinical research. Although the oxygen concentration distribution in a vessel could be obtained from a three-dimensional (3D) numerical simulation of blood flow coupled with oxygen transport, a 3D numerical simulation of the systemic arterial tree is complicated and requires considerable computational resources and time. However, the lumped parameter model of oxygen transport derived from transmission line equations of oxygen transport requires fewer computational resources and less time to numerically predict the oxygen concentration distribution in the systemic arterial tree. In this study, transmission line equations of oxygen transport are developed according to the theory of oxygen transport in the vessel, and fluid transmission line equations are used as the theoretical reference for the development. The transmission line equations of oxygen transport could also be regarded as the theoretical basis for developing lumped parameter models of other substances in blood.
URI: http://hdl.handle.net/10397/79931
EISSN: 2045-2322
DOI: 10.1038/s41598-018-23743-2
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