Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/79134
Title: Thermoresponsive hydrogels and their biomedical applications : special insight into their applications in textile based transdermal therapy
Authors: Chatterjee, S 
Hui, PCL 
Kan, C 
Keywords: Biomedical application
Drug delivery
Natural polymer
Textile
Thermoresponsive hydrogel
Transdermal therapy
Issue Date: 2018
Publisher: Molecular Diversity Preservation International (MDPI)
Source: Polymers, 2018, v. 10, no. 5, 480 How to cite?
Journal: Polymers 
Abstract: Various natural and synthetic polymers are capable of showing thermoresponsive properties and their hydrogels are finding a wide range of biomedical applications including drug delivery, tissue engineering and wound healing. Thermoresponsive hydrogels use temperature as external stimulus to show sol-gel transition and most of the thermoresponsive polymers can form hydrogels around body temperature. The availability of natural thermoresponsive polymers and multiple preparation methods of synthetic polymers, simple preparation method and high functionality of thermoresponsive hydrogels offer many advantages for developing drug delivery systems based on thermoresponsive hydrogels. In textile field applications of thermoresponsive hydrogels, textile based transdermal therapy is currently being applied using drug loaded thermoresponsive hydrogels. The current review focuses on the preparation, physico-chemical properties and various biomedical applications of thermoresponsive hydrogels based on natural and synthetic polymers and especially, their applications in developing functionalized textiles for transdermal therapies. Finally, future prospects of dual responsive (pH/temperature) hydrogels made by these polymers for textile based transdermal treatments are mentioned in this review.
URI: http://hdl.handle.net/10397/79134
ISSN: 2073-4360
DOI: 10.3390/polym10050480
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