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|Title:||Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese||Authors:||Lee, JWY
|Keywords:||Primary open angle glaucoma
Selective laser trabeculoplasty
|Issue Date:||9-Sep-2014||Publisher:||Dove Medical Press Limited||Source:||Clinical ophthalmology, 9 Sept. 2014, v. 8, p. 1788-1791 How to cite?||Journal:||Clinical ophthalmology||Abstract:||Purpose: To determine the predictors of success for adjuvant selective laser trabeculoplasty (SLT) in Chinese primary open angle glaucoma (POAG) patients.
Methods: This prospective study recruited Chinese subjects with unilateral or bilateral POAG currently taking medication to reduce intraocular pressure (IOP). All subjects received a single session of 360° SLT treatment and continued their medications for 1 month. SLT success was defined as IOP reduction ≥20% at 1 month. The following covariates were analyzed in both groups via univariate and multivariate analyses: age, sex, lens status, initial IOPs, post-SLT IOPs, number and type of medications, SLT shots and energy, and pre-SLT investigations.
Results: In 51 eyes of 33 POAG subjects, the success rate of SLT was 47.1%. Certain groups of patients were associated with greater success using univariate analysis. These groups included the following: older age (coefficient =0.1; OR: 1.1; P=0.0003), a higher pre-SLT IOP (coefficient =0.3; OR: 1.3; P=0.0005), using four types of antiglaucoma medication (coefficient =2.1; OR: 8.4; P=0.005), a greater degree of spherical equivalent (coefficient =2.1; OR: 8.4; P=0.005), and the use of a topical carbonic anhydrase inhibitor (coefficient =1.7; OR: 6.0; P=0.003). None of the covariates were significant using multivariate analysis.
Conclusion: Older age, a higher pretreatment IOP, using multiple antiglaucoma medications especially topical carbonic anhydrase inhibitor, and higher refractive errors were associated with greater SLT success.
|URI:||http://hdl.handle.net/10397/7579||ISSN:||1177-5483||DOI:||10.2147/OPTH.S69166||Rights:||© 2014 Lee et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php
The following publication Lee, J. W., Liu, C. C., Chan, J. C., Wong, R. L., Wong, I. Y., & Lai, J. S. (2014). Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese. Clinical ophthalmology, 8, 1787-1791 is available at http://dx.doi.org/10.2147/OPTH.S69166
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