Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/7570
Title: Carbon nanotube composites for glucose biosensor incorporated with reverse iontophoresis function for noninvasive glucose monitoring
Authors: Sun, TP
Shieh, HL
Ching, CTS
Yao, YD
Huang, SH
Liu, CM
Liu, WH
Chen, CY
Keywords: Amperometric
Carbon nanotubes
Glucose monitoring
Biosensors
Reverse iontophoresis
Issue Date: May-2010
Publisher: Dove Medical Press
Source: International journal of nanomedicine, May 2010, v. 2010:5, p. 343-349 How to cite?
Journal: International journal of nanomedicine 
Abstract: This study aims to develop an amperometric glucose biosensor, based on carbon nanotubes material for reverse iontophoresis, fabricated by immobilizing a mixture of glucose oxidase (GOD) and multiwalled carbon nanotubes (MWCNT) epoxy-composite, on a planar screen-printed carbon electrode. MWCNT was employed to ensure proper incorporation into the epoxy mixture and faster electron transfer between the GOD and the transducer. Results showed this biosensor possesses a low detection potential (+500 mV), good sensitivity (4 μA/mM) and an excellent linear response range (r² = 0.999; 0–4 mM) of glucose detection at +500 mV (versus Ag/AgCl). The response time of the biosensor was about 25 s. In addition, the biosensor could be used in conjunction with reverse iontophoresis technique. In an actual evaluation model, an excellent linear relationship (r² = 0.986) was found between the glucose concentration of the actual model and the biosensor’s current response. Thus, a glucose biosensor based on carbon nanotube composites and incorporated with reverse iontophoresis function was developed.
URI: http://hdl.handle.net/10397/7570
ISSN: 1176-9114
EISSN: 1178-2013
Rights: © 2010 Sun et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
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