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http://hdl.handle.net/10397/7568
Title: | Image-guided radiation therapy using computed tomography in radiotherapy | Authors: | Fung, WWK Wu, VWC |
Issue Date: | 2011 | Source: | Journal of radiotherapy in practice, 2011, v. 10, no. 2, p. 121-136 | Abstract: | The sharp dose gradients in intensity-modulated radiation therapy increase the treatment sensitivity to various inter- and intra-fractional uncertainties, in which a slight anatomical change may greatly alter the actual dose delivered. Image-guided radiotherapy refers to the use of advanced imaging techniques to precisely track and correct these patient-specific variations in routine treatment. It can also monitor organ changes during a radiotherapy course. Currently, image-guided radiotherapy using computed tomography has gained much popularity in radiotherapy verification as it provides volumetric images with soft-tissue contrast for on-line tracking of tumour. This article reviews four types of computed tomography-based image guidance systems and their working principles. The system characteristics and clinical applications of the helical, megavoltage, computed tomography, and kilovoltage, cone-beam, computed tomography systems are discussed, given that they are currently the most commonly used systems for radiotherapy verification. This article also focuses on the recent techniques of soft-tissue contrast enhancement, digital tomosynthesis, four-dimensional fluoroscopic image guidance, and kilovoltage/megavoltage, in-line cone-beam imaging. These evolving systems are expected to take over the conventional two-dimensional verification system in the near future and provide the basis for implementing adaptive radiotherapy. | Keywords: | Image-guided RT Treatment verification Inter-fractional uncertainties Computed tomography |
Journal: | Journal of radiotherapy in practice | ISSN: | 1460-3969 | DOI: | 10.1017/S1460396910000270 |
Appears in Collections: | Journal/Magazine Article |
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Fung_Image-guided_Radiation_Therapy.pdf | 114.33 kB | Adobe PDF | View/Open |
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