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http://hdl.handle.net/10397/74766
Title: | Increase in the prevalence of hypertension among adults exposed to the Great Chinese Famine during early life | Authors: | Liu, L Xu, X Zeng, H Zhang, Y Shi, Z Zhang, F Cao, X Xie, YJ Reis, C Zhao, Y |
Issue Date: | 2017 | Source: | Environmental health and preventive medicine, 2017, v. 22, 64, p. 1-7 | Abstract: | Objective: This study aimed to assess the association between exposure to the Great Chinese Famine (1959-1961) during early life and hypertension in adulthood. Methods: From July to September 2009, 1224 eligible adults were recruited in a cross-sectional survey using a multi-stage stratified random sampling method in Chongqing China. A questionnaire was used to collect information of hypertension and sociodemographic factors. Participants were categorized as childhood, fetal, and none exposure to famine based on the date of birth. Results: Of the sample, 12.3% reported having hypertension. The prevalence of hypertension varied by famine status: 11.9% in childhood exposure, 16.1% in fetal exposure, and 10.2% in non-exposure group. After adjusting for sociodemographic and lifestyle factors, compared with non-exposure group, fetal exposure group had an increased likelihood of having hypertension with odds ratio of 1.79 (95%CI 1.13-2.84). Although there was no significant gender and famine interaction, the positive association between famine exposure and hypertension was stronger among women than men. Conclusion: Fetal exposure to the Chinese famine may be associated with an increased risk of arthritis in adulthood in women. | Keywords: | Adulthood Childhood Chinese famine Hypertension Malnutrition |
Publisher: | BioMed Central Ltd. | Journal: | Environmental health and preventive medicine | ISSN: | 1342-078X | EISSN: | 1347-4715 | DOI: | 10.1186/s12199-017-0671-2 | Rights: | © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. The following publication Liu, L., Xu, X., Zeng, H., Zhang, Y., Shi, Z., Zhang, F., … Zhao, Y. (2017). Increase in the prevalence of hypertension among adults exposed to the Great Chinese Famine during early life. Environmental Health and Preventive Medicine, 22, 64, 1-7 is available at https://dx.doi.org/10.1186/s12199-017-0671-2 |
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