Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/74419
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Biomedical Engineering | en_US |
dc.creator | Chan, PMB | en_US |
dc.creator | Wen, C | en_US |
dc.creator | Yang, WC | en_US |
dc.creator | Yan, C | en_US |
dc.creator | Chiu, K | en_US |
dc.date.accessioned | 2018-03-29T07:16:46Z | - |
dc.date.available | 2018-03-29T07:16:46Z | - |
dc.identifier.issn | 0306-9877 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/74419 | - |
dc.language.iso | en | en_US |
dc.publisher | Churchill Livingstone | en_US |
dc.rights | © 2017 Elsevier Ltd. All rights reserved. | en_US |
dc.rights | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
dc.rights | The following publication Chan, P. M. B., Wen, C., Yang, W. C., Yan, C., & Chiu, K. (2017). Is subchondral bone cyst formation in non-load-bearing region of osteoarthritic knee a vascular problem?. Medical Hypotheses, 109, 80-83 is available at https://doi.org/10.1016/j.mehy.2017.09.027 | en_US |
dc.title | Is subchondral bone cyst formation in non-load-bearing region of osteoarthritic knee a vascular problem? | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 80 | en_US |
dc.identifier.epage | 83 | en_US |
dc.identifier.volume | 109 | en_US |
dc.identifier.doi | 10.1016/j.mehy.2017.09.027 | en_US |
dcterms.abstract | Subchondral bone cyst is common in the progressive knee osteoarthritis yet its underlying mechanism remains unclear. In addition to the existing theories such as synovial fluid influx and mechanical contusion, we identified the potential link between vascular pathology and osteoarthritic bone pathologies including cystic lesion formation, particularly in the non-load-bearing region. This new hypothesis for SBC formation in non-load-bearing region for knee, which cannot be explained by the existing theories, will provide us a new angle to understand the pathomechanism and pathophysiology of subchondral bone disturbance in osteoarthritis in addition to the classical biomechanical overloading theories. It might guide us to develop a novel diagnostic and therapeutic approach to treat progressive osteoarthritis via targeting vascular pathology. | en_US |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Medical hypotheses, Nov. 2017, v. 109, p. 80-83 | en_US |
dcterms.isPartOf | Medical hypotheses | en_US |
dcterms.issued | 2017-11 | - |
dc.identifier.scopus | 2-s2.0-85030327822 | - |
dc.identifier.eissn | 1532-2777 | en_US |
dc.identifier.rosgroupid | 2017000556 | - |
dc.description.ros | 2017-2018 > Academic research: refereed > Publication in refereed journal | en_US |
dc.description.validate | 201802 bcrc | en_US |
dc.description.oa | Accepted Manuscript | en_US |
dc.identifier.FolderNumber | BME-0180 | - |
dc.description.fundingSource | RGC | en_US |
dc.description.fundingSource | Others | en_US |
dc.description.fundingText | Li Shu Fan Medical Foundation Endowed Professorship in Orthopaedic Surgery; Hong Kong Research Grants Council | en_US |
dc.description.pubStatus | Published | en_US |
dc.identifier.OPUS | 15492013 | - |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Chan_Subchondral_Bone_Cyst.pdf | Pre-Published version | 2.78 MB | Adobe PDF | View/Open |
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