Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/68223
Title: On relationship of Z-curve and fourier approaches for DNA coding sequence classification
Authors: Law, NF 
Cheng, KO
Siu, WC 
Keywords: Z-Curve approach
FT analysis
DNA sequence
Coding region
Spectral analysis
Issue Date: 2006
Publisher: Biomedical Informatics Publishing Group
Source: Bioinformation, 2006, v. 1, no. 7, p. 242-246 How to cite?
Journal: Bioinformation 
Abstract: Z-curve features are one of the popular features used in exon/intron classification. We showed that although both Z-curve and Fourier approaches are based on detecting 3-periodicity in coding regions, there are significant differences in their spectral formulation. From the spectral formulation of the Z-curve, we obtained three modified sequences that characterize different biological properties. Spectral analysis on the modified sequences showed a much more prominent 3-periodicity peak in coding regions than the Fourier approach. For long sequences, prominent peaks at 2Π/3 are observed at coding regions, whereas for short sequences, clearly discernible peaks are still visible. Better classification can be obtained using spectral features derived from the modified sequences.
URI: http://hdl.handle.net/10397/68223
ISSN: 0973-2063
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