Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/6586
Title: Non-invasive blood glucose measurement by near infrared spectroscopy : machine drift, time drift and physiological effect
Authors: Lam, SCH
Chung, J
Fan, KL
Wong, TKS
Keywords: Spectroscopy
Machine drift
Time drift
Physiological effect
PLS
PDS
Beer's law
Issue Date: 2010
Publisher: Hindawi Publishing Corporation
Source: Spectroscopy, 2010, v. 24, no. 6, p. 629-639 How to cite?
Journal: Spectroscopy 
Abstract: The aim of this paper is to evaluate development of the non-invasive blood glucose measurement of near infrared (NIR) spectroscopy. The results showed that NIR spectroscopy might obtain glucose concentration of up to 200% difference under a same environmental condition with two months apart due to time and machine drifts. These effects can restrict the development of the non-invasive blood glucose measurement. Partial least square (PLS) regression was used, which showed advantage over using simple absorbance for glucose concentration. Non-invasive blood glucose measurement of health subjects (non-diabetics) was also investigated. The results showed that R correlation coefficient of prediction (Rp) was 0.48 and root mean square of prediction (rmsep) was 1.34 mmol/l. The error was mainly due to the physiological effect of different subjects.
URI: http://hdl.handle.net/10397/6586
ISSN: 0712-4813 (print)
1875-922X (online)
DOI: 10.3233/SPE-2010-0485
Rights: Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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