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Title: Vascular contributions to cognitive impairment and treatments with traditional Chinese medicine
Authors: Zhou, X
Cui, G
Tseng, HHL
Lee, SMY
Leung, GPH 
Chan, SW 
Kwan, YW
Hoi, MPM
Issue Date: 2016
Publisher: Hindawi Publishing Corporation
Source: Evidence-based complementary and alternative medicine, 2016, v. 2016, 9627258 How to cite?
Journal: Evidence-based complementary and alternative medicine 
Abstract: The prevalence of cognitive impairment and dementia caused by cerebrovascular disease is likely to increase with the global aging population. Vascular contributions to cognitive impairment and dementia (VCID) is a wide spectrum term used to include a diverse heterogeneous group of cognitive syndromes with vascular factors regardless of the cause of pathogenesis. VCID ranges from mild cognitive impairment to full-blown dementia with vascular dementia (VaD) as the most severe stage. It is further complexed by the coexistence of other forms of dementia such as Alzheimer's disease (AD). Recent researches in the functions of the neurovascular unit (NVU) suggest that dysfunction of the NVU might be the cause of primary vascular events in the brain that leads to further neurodegeneration. In this review, we have briefly summarized various forms of VCID. There is currently no standard therapy for VCID or dementia. Given the fact that Traditional Chinese Medicine (TCM) has gained popularity worldwide, we also reviewed recent scientific and clinical findings on various antidementia TCM for the treatment of VCID, including Salvia miltiorrhiza, Huperzia serrata, Ligusticum chuanxiong, Ginkgo biloba, Panax ginseng, and also TCM formula Sailuotong capsule (SLT) and Fufangdanshen tablets (FFDS).
ISSN: 1741-427X
EISSN: 1741-4288
DOI: 10.1155/2016/9627258
Rights: Copyright © 2016 Xinhua Zhou et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The following article: Zhou, X., Cui, G., Tseng, H. H. L., Lee, S. M. Y., Leung, G. P. H., Chan, S. W., ... & Hoi, M. P. M. (2016). Vascular contributions to cognitive impairment and treatments with traditional Chinese medicine. Evidence-Based Complementary and Alternative Medicine, 2016, is available at https//
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