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Title: Baroreceptor reflex in heart failure
Other Titles: 心力衰竭状态下的动脉压力感受器反射 (英文)
Authors: Wang, W
Zhu, GQ
Gao, L
Tan, W
Qian, ZM
Keywords: Baroreceptor reflex
Chemoreceptor reflex
Heart failure
Angiotensin Ⅱ
Reactive oxygen species
Exercise training
Issue Date: 2004
Publisher: 科學出版社
Source: 生理学报 (Acta physiological sinica), June 2004, v. 56, no. 3, p. 269-281 How to cite?
Journal: 心理学报 (Acta psychologica sinica) 
Abstract: Congestive heart failure is a syndrome that is usually initiated by a reduction in pump function of the heart, i.e. a decrease incardiac output. Initially, a reduction in cardiac output leads to unloading of baroreceptor reflex that, in turn, increases heart rate throughvago-sympathetic mechanisms and total peripheral resistance via an increase in sympathetic outflow to vascular beds. In this review weare thinking on how baroreceptor reflex plays a role in the abnormal control of the circulation in heart failure. This review and our recentstudies suggest that: (1) baroreceptor reflex is blunted in heart failure; (2) central angiotensin Ⅱ and reactive oxygen species play animportant role in blunted baroreceptor reflex; (3) cardiac sympathetic afferent stimulation and chemoreceptor reflex inhibit baroreceptorreflex; and (4) exercise training normalizes abnormal reflexes in the heart failure state.
ISSN: 0439-755X
Rights: © 2004 中国学术期刊电子杂志出版社。本内容的使用仅限于教育、科研之目的。
© 2004 China Academic Journal Electronic Publishing House. It is to be used strictly for educational and research purposes.
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