Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/61365
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dc.contributorDepartment of Health Technology and Informaticsen_US
dc.creatorYing, Men_US
dc.creatorCheng, SCHen_US
dc.creatorAhuja, ATen_US
dc.date.accessioned2016-12-19T08:55:37Z-
dc.date.available2016-12-19T08:55:37Z-
dc.identifier.issn0301-5629en_US
dc.identifier.urihttp://hdl.handle.net/10397/61365-
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rights© 2016 World Federation for Ultrasound in Medicine & Biologyen_US
dc.rights© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.rightsThe following publication Ying, M., Cheng, S. C., & Ahuja, A. T. (2016). Diagnostic accuracy of computer-aided assessment of intranodal vascularity in distinguishing different causes of cervical lymphadenopathy. Ultrasound in medicine & biology, 42(8), 2010-2016 is available at https://doi.org/10.1016/j.ultrasmedbio.2016.03.014.en_US
dc.subjectBlood vesselsen_US
dc.subjectComputer assisteden_US
dc.subjectImage processingen_US
dc.subjectLymph nodesen_US
dc.subjectPower Doppleren_US
dc.subjectUltrasonographyen_US
dc.subjectVascularity indexen_US
dc.titleDiagnostic accuracy of computer-aided assessment of intranodal vascularity in distinguishing different causes of cervical lymphadenopathyen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage2010en_US
dc.identifier.epage2016en_US
dc.identifier.volume42en_US
dc.identifier.issue8en_US
dc.identifier.doi10.1016/j.ultrasmedbio.2016.03.014en_US
dcterms.abstractUltrasound is useful in assessing cervical lymphadenopathy. Advancement of computer science technology allows accurate and reliable assessment of medical images. The aim of the study described here was to evaluate the diagnostic accuracy of computer-aided assessment of the intranodal vascularity index (VI) in differentiating the various common causes of cervical lymphadenopathy. Power Doppler sonograms of 347 patients (155 with metastasis, 23 with lymphoma, 44 with tuberculous lymphadenitis, 125 reactive) with palpable cervical lymph nodes were reviewed. Ultrasound images of cervical nodes were evaluated, and the intranodal VI was quantified using a customized computer program. The diagnostic accuracy of using the intranodal VI to distinguish different disease groups was evaluated and compared. Metastatic and lymphomatous lymph nodes tend to be more vascular than tuberculous and reactive lymph nodes. The intranodal VI had the highest diagnostic accuracy in distinguishing metastatic and tuberculous nodes with a sensitivity of 80%, specificity of 73%, positive predictive value of 91%, negative predictive value of 51% and overall accuracy of 68% when a cutoff VI of 22% was used. Computer-aided assessment provides an objective and quantitative way to evaluate intranodal vascularity. The intranodal VI is a useful parameter in distinguishing certain causes of cervical lymphadenopathy and is particularly useful in differentiating metastatic and tuberculous lymph nodes. However, it has limited value in distinguishing lymphomatous nodes from metastatic and reactive nodes.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationUltrasound in medicine and biology, Aug. 2016, v. 42, no. 8, p. 2010-2016en_US
dcterms.isPartOfUltrasound in medicine and biologyen_US
dcterms.issued2016-08-
dc.identifier.isiWOS:000378389000029-
dc.identifier.scopus2-s2.0-84964597367-
dc.identifier.pmid27131839-
dc.identifier.ros2016002530-
dc.identifier.eissn1879-291Xen_US
dc.identifier.rosgroupid2016002478-
dc.description.ros2016-2017 > Academic research: refereed > Publication in refereed journalen_US
dc.description.validate201804_a bcmaen_US
dc.description.oaAccepted Manuscripten_US
dc.identifier.FolderNumberHTI-0144-
dc.description.fundingSourceSelf-fundeden_US
dc.description.pubStatusPublisheden_US
dc.identifier.OPUS6688427-
dc.description.oaCategoryGreen (AAM)en_US
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