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http://hdl.handle.net/10397/61324
Title: | Natural products from Chinese medicines with potential benefits to bone health | Authors: | Che, CT Wong, MS Lam, CWK |
Issue Date: | Mar-2016 | Source: | Molecules, Mar. 2016, v. 21, no. 3, 239, p. 1-52 | Abstract: | Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass and microstructure, leading to reduced bone strength and increased risk of fracture. It is often associated with reduced quality of life and other medical complications. The disease is common in the aging population, particularly among postmenopausal women and patients who receive long-term steroidal therapy. Given the rapid growth of the aging population, increasing life expectancy, the prevalence of bone loss, and financial burden to the healthcare system and individuals, demand for new therapeutic agents and nutritional supplements for the management and promotion of bone health is pressing. With the advent of global interest in complementary and alternative medicine and natural products, Chinese medicine serves as a viable source to offer benefits for the improvement and maintenance of bone health. This review summarizes the scientific information obtained from recent literatures on the chemical ingredients of Chinese medicinal plants that have been reported to possess osteoprotective and related properties in cell-based and/or animal models. Some of these natural products (or their derivatives) may become promising leads for development into dietary supplements or therapeutic drugs. | Keywords: | Anti-osteoporosis Bone health Chinese medicine Natural product Osteoprotection |
Publisher: | Molecular Diversity Preservation International (MDPI) | Journal: | Molecules | ISSN: | 1420-3049 | DOI: | 10.3390/molecules21030239 | Rights: | © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). The following publication Che, C.-T.; Wong, M.S.; Lam, C.W.K. Natural Products from Chinese Medicines with Potential Benefits to Bone Health. Molecules 2016, 21, 239, 1-52 is available at https://dx.doi.org/10.3390/molecules21030239 |
Appears in Collections: | Journal/Magazine Article |
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