Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/60258
Title: 铁代谢与铁调素hepcidin
Authors: Fu, LJ
Duan, XL
Qian, ZM
Issue Date: 2005
Publisher: 中國生理科學會
Source: 生理科学进展 (Progress in physiological sciences), 2005, v. 36, no. 3, p. 233-236 How to cite?
Journal: 生理科学进展 (Progress in physiological sciences) 
Abstract: 铁是机体必需的营养元素。然而,铁过载则导致细胞的损伤。由于生物体缺少排泄铁的机制,因而,肠铁吸收的调控便成为维持机体铁稳态的关键。新近研究发现hepcidin对机体铁稳态的调节起着至关重要的作用,被人们称为铁调节激素。Hepcidin主要在肝细胞中合成,之后分泌至血液将体内铁需要的信号传至小肠,调控肠铁的吸收。这一过程主要通过调节小肠铁转运相关蛋白的表达而实现。任何影响hepcidin表达的因素都可能破坏体内的铁平衡,造成铁代谢相关疾病。
URI: http://hdl.handle.net/10397/60258
ISSN: 0559-7765
Rights: © 2005 中国学术期刊电子杂志出版社。本内容的使用仅限于教育、科研之目的。
© 2005 China Academic Journal Electronic Publishing House. It is to be used strictly for educational and research purposes.
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