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Title: Influence of pyridine substitufive derivation to metabolic pathway of blakeslea trispora
Other Titles: 吡啶类化合物对三孢布拉氏霉菌代谢途径的影响
Authors: Wang, JD
Wang, YS
Yuan, QP
Zhang, Q
Qian, ZM
Keywords: Lycopene
Blakeslea trispora
Blocking agent
Issue Date: 2003
Publisher: 化学工业部科技情报硏究所
Source: 現代化工 (Modern Chemical Industry), 2003, v. 23, no. S1, p. 202-204 How to cite?
Journal: 現代化工 (Modern Chemical Industry) 
Abstract: 利用β-胡萝卜素高产菌株三孢布拉氏霉菌(Blakeslea trispora)发酵生产番茄红素过程中,可通过突变菌株或中途加入阻断剂的方法,将代谢控制在番茄红素水平。主要考察了吡啶衍生物如2,6-二甲基吡啶、2,5-二甲基吡啶、2-氨基-6-甲基吡啶及烟草废弃物(主要成分为3-吡啶基衍生物)对三孢布拉氏霉菌代谢途径的影响。结果表明:1.0g/L的 2,6-二甲基吡啶阻断效果最好,大量积累番茄红素,几乎无β-胡萝卜素生成;加入的烟草废弃物浓度为 15g/L时,有少量β-胡萝卜素生成,番茄红素含量较前者提高58%,达到 1 090.03 mg/L。
Lycopene can be biosynthesized by adding blocking agents to Blakeslea trispora which can produce β-carotenewith high yield or by employing mutant strain of Blakeslea trispora. The effects of pyridine substitutive derivations on themetabolic pathway of Blakeslea trispora, were studied sueh as 2, 6-dimethylpyridine, 2, 5-dimethylpyridine, 2-amino-6-methylpyridine and tobacco dust which contains mainly 3-pyridine substitutive derivation. As a result, it is completely possible toachieve only lycopene almost without β-carotene in the presence of 2-amino-6-methylpyridine whose concentration is up to 1. 0g/L. When the concentration of tobacco dust employed in medium reaches 15g/L, the yield of lycopene is 58% higher than theformer, climbing to 1 090. 03 mg/L, and there is little β-carotene obtained simultaneously. 还原
ISSN: 0253-4320
DOI: 10.16606/j.cnki.issn0253-4320.2003.s1.060
Rights: © 2003 中国学术期刊电子杂志出版社。本内容的使用仅限于教育、科研之目的。
© 2003 China Academic Journal Electronic Publishing House. It is to be used strictly for educational and research purposes.
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