Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/60249
PIRA download icon_1.1View/Download Full Text
Title: Influence of pyridine substitufive derivation to metabolic pathway of blakeslea trispora
Other Title: 吡啶类化合物对三孢布拉氏霉菌代谢途径的影响
Authors: Wang, JD
Wang, YS
Yuan, QP
Zhang, Q
Qian, ZM
Issue Date: 2003
Source: 現代化工 (Modern Chemical Industry), 2003, v. 23, no. S1, p. 202-204
Abstract: 利用β-胡萝卜素高产菌株三孢布拉氏霉菌(Blakeslea trispora)发酵生产番茄红素过程中,可通过突变菌株或中途加入阻断剂的方法,将代谢控制在番茄红素水平。主要考察了吡啶衍生物如2,6-二甲基吡啶、2,5-二甲基吡啶、2-氨基-6-甲基吡啶及烟草废弃物(主要成分为3-吡啶基衍生物)对三孢布拉氏霉菌代谢途径的影响。结果表明:1.0g/L的 2,6-二甲基吡啶阻断效果最好,大量积累番茄红素,几乎无β-胡萝卜素生成;加入的烟草废弃物浓度为 15g/L时,有少量β-胡萝卜素生成,番茄红素含量较前者提高58%,达到 1 090.03 mg/L。
Lycopene can be biosynthesized by adding blocking agents to Blakeslea trispora which can produce β-carotenewith high yield or by employing mutant strain of Blakeslea trispora. The effects of pyridine substitutive derivations on themetabolic pathway of Blakeslea trispora, were studied sueh as 2, 6-dimethylpyridine, 2, 5-dimethylpyridine, 2-amino-6-methylpyridine and tobacco dust which contains mainly 3-pyridine substitutive derivation. As a result, it is completely possible toachieve only lycopene almost without β-carotene in the presence of 2-amino-6-methylpyridine whose concentration is up to 1. 0g/L. When the concentration of tobacco dust employed in medium reaches 15g/L, the yield of lycopene is 58% higher than theformer, climbing to 1 090. 03 mg/L, and there is little β-carotene obtained simultaneously. 还原
Keywords: Lycopene
Pyridine
Blakeslea trispora
Blocking agent
Publisher: 化学工业部科技情报硏究所
Journal: 現代化工 (Modern Chemical Industry) 
ISSN: 0253-4320
DOI: 10.16606/j.cnki.issn0253-4320.2003.s1.060
Rights: © 2003 中国学术期刊电子杂志出版社。本内容的使用仅限于教育、科研之目的。
© 2003 China Academic Journal Electronic Publishing House. It is to be used strictly for educational and research purposes.
Appears in Collections:Journal/Magazine Article

Files in This Item:
File Description SizeFormat 
r14160.pdf264.8 kBAdobe PDFView/Open
Open Access Information
Status open access
File Version Version of Record
Access
View full-text via PolyU eLinks SFX Query
Show full item record

Page views

110
Last Week
1
Last month
Citations as of Mar 24, 2024

Downloads

30
Citations as of Mar 24, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.