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http://hdl.handle.net/10397/5856
Title: | A review of the phytochemistry and pharmacological activities of Raphani Semen | Authors: | Sham, TT Yuen, ACY Ng, YF Chan, CO Mok, DKW Chan, SW |
Issue Date: | 2013 | Source: | Evidence-based complementary and alternative medicine, 2013, v. 2013, 636194, p. 1-16 | Abstract: | The dried ripe seed of Raphanus sativus L., commonly known as radish seed (or Raphani Semen), is used as traditional Chinese medicine (TCM) to treat constipation, chronic tracheitis, and hypertension.The major active compounds in Raphani Semen are alkaloids, glucosinolates, brassinosteroids, and flavonoids. Fatty acids are its main nutritional contents. Raphani Semen has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough. So far, there is no report about the adverse/toxic effects of this herb on humans. However, Raphani Semen processed by roasting was reported to exhibit some adverse effects on mice. Additionally, erucic acid, the main fatty acid in Raphani Semen, was shown to enhance the toxicity of doxorubicin. Thus, Raphani Semen has a potential risk of causing toxicity and drug interaction. In summary, Raphani Semen is a valuable TCMherb withmultiple pharmacological effects.More studies on Raphani Semen could help better understand its pharmacological mechanisms so as to provide clear scientific evidence to explain its traditional uses, to identify its therapeutic potential on other diseases, and to understand its possible harmful effects. | Publisher: | Hindawi Publishing Corporation | Journal: | Evidence-based complementary and alternative medicine | ISSN: | 1741-427X | EISSN: | 1741-4288 | DOI: | 10.1155/2013/636194 | Rights: | Copyright © 2013 Tung-Ting Sham et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Appears in Collections: | Journal/Magazine Article |
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eCAM-2013 (1).pdf | 2.66 MB | Adobe PDF | View/Open |
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