Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/5856
Title: A review of the phytochemistry and pharmacological activities of Raphani Semen
Authors: Sham, TT
Yuen, ACY
Ng, YF
Chan, CO
Mok, DKW 
Chan, SW
Issue Date: 2013
Publisher: Hindawi Publishing Corporation
Source: Evidence-based complementary and alternative medicine, 2013, v. 2013, 636194, p. 1-16 How to cite?
Journal: Evidence-based complementary and alternative medicine 
Abstract: The dried ripe seed of Raphanus sativus L., commonly known as radish seed (or Raphani Semen), is used as traditional Chinese medicine (TCM) to treat constipation, chronic tracheitis, and hypertension.The major active compounds in Raphani Semen are alkaloids, glucosinolates, brassinosteroids, and flavonoids. Fatty acids are its main nutritional contents. Raphani Semen has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough. So far, there is no report about the adverse/toxic effects of this herb on humans. However, Raphani Semen processed by roasting was reported to exhibit some adverse effects on mice. Additionally, erucic acid, the main fatty acid in Raphani Semen, was shown to enhance the toxicity of doxorubicin. Thus, Raphani Semen has a potential risk of causing toxicity and drug interaction. In summary, Raphani Semen is a valuable TCMherb withmultiple pharmacological effects.More studies on Raphani Semen could help better understand its pharmacological mechanisms so as to provide clear scientific evidence to explain its traditional uses, to identify its therapeutic potential on other diseases, and to understand its possible harmful effects.
URI: http://hdl.handle.net/10397/5856
ISSN: 1741-427X
EISSN: 1741-4288
DOI: 10.1155/2013/636194
Rights: Copyright © 2013 Tung-Ting Sham et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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