Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/5830
Title: Orienting attention modulates pain perception : an ERP study
Authors: Chan, SCC 
Chan, CCH 
Kwan, ASK
Ting, KH
Chui, TY
Keywords: Event-related potentials
Laser-evoked-potentials
Go/nogo task
Response-inhibition
Stimulus probability
Neural mechanisms
Spatial attention
Cingulate cortex
Stroop task
Brain
Issue Date: 29-Jun-2012
Publisher: Public Library of Science
Source: PLoS one, 29 June, 2012, v. 7, no. 6, e40215, p. 1-12 How to cite?
Journal: PLoS one 
Abstract: Introduction: Research has shown that people with chronic pain have difficulty directing their attention away from pain. A mental strategy that incorporates focused attention and distraction has been found to modulate the perception of pain intensity. That strategy involves placing attention on the nociceptive stimulus felt and shifting attention to a self-generated sub-nociceptive image and rehearsing it. Event-related potential was used to study the possible processes associated with the focus-then-orient strategy.
Methods: Eighteen pain-free participants received different levels of 50-ms nociceptive stimulations elicited by electric shocks at the right lateral malleolus (ankle). In perception trials, participants maintained the perceived nociceptive stimulus in working memory for 3,000 ms. In imagery trials, participants mentally generated and maintained the corresponding sub-nociceptive image they had learned previously. After both types of trials, participants evaluated the pain intensity of the incoming stimulus by recalling the feeling of the nociceptive stimulation at the beginning of the trial.
Results: Shifting attention from the incoming nociceptive to a self-generated sub-nociceptive image elicited central P2 and centro-parietal P3 waves, which were found to correlate with proportional scores on the Stroop Test. They were followed by a frontal N400 and a parietal P600, denoting generation of sub-nociceptive images in working memory. The voltages elicited in these potentials correlated moderately with attenuation of the pain ratings of the recalled nociceptive stimulations.
Conclusions: Focus-and-orient attention across nociceptive and sub-nociceptive images appears to be related to response inhibition. Mental rehearsal of the sub-nociceptive images was found to modulate the perception of the nociceptive sensation felt prior to the imagery. Such modulation seems to be mediated by generating and maintaining sub-nociceptive images in working memory. Future studies should explore the mental processes associated with orienting attention for pain modulation among people with pathological pain and frontal lobe dysfunction.
URI: http://hdl.handle.net/10397/5830
EISSN: 1932-6203
DOI: 10.1371/journal.pone.0040215
Rights: © 2012 Chan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Appears in Collections:Journal/Magazine Article

Files in This Item:
File Description SizeFormat 
Chan_Modulates_Pain_Perception.pdf329.55 kBAdobe PDFView/Open
Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

14
Last Week
0
Last month
1
Citations as of Aug 20, 2017

WEB OF SCIENCETM
Citations

13
Last Week
0
Last month
0
Citations as of Aug 20, 2017

Page view(s)

297
Last Week
0
Last month
Checked on Aug 20, 2017

Download(s)

130
Checked on Aug 20, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.