Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/34768
Title: Cumulative effects of hypertension, dyslipidemia, and chronic kidney disease on carotid atherosclerosis in Chinese patients with type 2 diabetes mellitus
Authors: Yuan, C 
Lai, CW 
Chan, LW 
Chow, M 
Law, HK 
Ying, M 
Issue Date: 2014
Publisher: Hindawi Publishing Corporation
Source: Journal of diabetes research, 2014, v. 2014, 179686, p. 1-7 How to cite?
Journal: Journal of diabetes research 
Abstract: Aims. The aim of this study is to determine the extent of carotid atherosclerosis in Chinese patients with type 2 diabetes in relation to the cumulative atherosclerosis risk factors using ultrasonography.
Methods. The presence of hypertension, dyslipidemia, and chronic kidney disease (CKD) was documented in 106 Chinese subjects with type 2 diabetes. Subjects with 0, 1, and ≥2 additional atherosclerosis risk factors were assigned into groups 1, 2, and 3, respectively (n=17, 49, and 40, resp.). Using ultrasound, the carotid arteries were assessed for the presence of carotid plaque, plaque score, intima-media thickness (IMT), and carotid arterial stiffness.
Results. With the adjustment for age and gender, the presence of plaque and plaque score were significantly higher in groups with more atherosclerosis risk factors (P<0.05). In addition, age > 60 years old (odds ratio = 2.75; 95% CI: 1.26–6.0) and the presence of hypertension (odds ratio = 2.48; 95% CI: 1.11–5.58), dyslipidemia (odds ratio = 2.41; 95% CI: 1.05–5.51), and CKD (odds ratio = 7.80; 95% CI: 1.46–41.72) could independently predict higher plaque score (P<0.05).
Conclusions. Hypertension, dyslipidemia, and CKD in Chinese patients with type 2 diabetes have cumulative effects on the burden of carotid plaque.
URI: http://hdl.handle.net/10397/34768
ISSN: 2314-6745
EISSN: 2314-6753
DOI: 10.1155/2014/179686
Rights: Copyright © 2014 Chuang Yuan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The following article: Yuan, C., Lai, C. W., Chan, L. W., Chow, M., Law, H. K., & Ying, M. (2014). Cumulative effects of hypertension, dyslipidemia, and chronic kidney disease on carotid atherosclerosis in Chinese patients with type 2 diabetes mellitus. Journal of diabetes research, 2014, is available at https//doi.org/10.1155/2014/179686
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