Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/30718
Title: Myopic children have central reduction in high contrast multifocal erg response, while adults have paracentral reduction in low contrast response
Authors: Ho, WC
Kee, CS 
Chan, HHL 
Issue Date: 2012
Publisher: Association for Research in Vision and Ophthalmology
Source: Investigative ophthalmology and visual science, 2012, v. 53, no. 7, p. 3695-3702 How to cite?
Journal: Investigative ophthalmology and visual science 
Abstract: PURPOSE. To compare the retinal function of myopic children and young adults using the multifocal electroretinogram (mfERG). METHODS. Fifty-two children (aged 9-14 years) and 19 young adults (aged 21-28 years) with spherical equivalent refractive errors ranging from plano to -5.50 diopter (D) were recruited. They were examined using the global flash mfERG at 49% and 96% contrasts. Each local mfERG response was pooled into five concentric rings for analysis. The amplitudes and implicit times of direct components (DC) and induced components (IC) from the global flash response were analyzed. Hierarchical multiple regressions were used to evaluate the influence of refractive error and axial length on the DC and IC responses. RESULTS. Compared with the emmetropes of the same age group, myopic children had a significant reduction in central macular DC response at 96% contrast while the IC response was unaffected, but myopic adults showed significant reductions in paracentral IC amplitudes at 49% contrast. Implicit times for DC and IC responses were unaffected for either group. CONCLUSIONS. Retinal function was unaffected in myopic children, except for the outer retina in the central macular region. In contrast, the inner retinal function was substantially reduced in myopic adults, especially in the paracentral region. This study provides further evidence for different retinal, physiological characteristics in myopic children and myopic adults.
URI: http://hdl.handle.net/10397/30718
ISSN: 0146-0404
EISSN: 1552-5783
DOI: 10.1167/iovs.11-9379
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

11
Last Week
1
Last month
0
Citations as of Nov 10, 2017

WEB OF SCIENCETM
Citations

5
Last Week
0
Last month
0
Citations as of Nov 15, 2017

Page view(s)

79
Last Week
1
Last month
Checked on Nov 19, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.