Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/16122
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Title: Corneal shapes of Chinese emmetropes and myopic astigmats aged 10 to 45 years
Authors: Leung, TW 
Lam, AKC 
Kee, CS 
Issue Date: Nov-2013
Source: Optometry and vision science, Nov. 2013, v. 90, no. 11, p. 1259-1266
Abstract: PURPOSE: Myopia and astigmatism are highly prevalent in the Hong Kong Chinese. This study aimed to determine the effects of age and myopic astigmatism (MA) on the corneal shape factors in the Hong Kong Chinese. METHODS: One hundred subjects with compound MA or emmetropia (EM) were recruited from three age groups: 10 to 15 years (n = 32), 20 to 25 years (n = 37), and 40 to 45 years (n = 31). Refractive errors were measured by noncycloplegic subjective refraction. Corneal astigmatism and corneal shape factors were measured by the Scheimpflug-based Pentacam. The effects of age and refractive errors on the whole corneal shape (mean-P) and the semimeridian corneal shapes (semi-Ps) at the nasal, temporal, superior, and inferior corneal quadrants (from corneal apex to 3 mm peripheral cornea) were analyzed. RESULTS: Age had significant effects on the mean-P and semi-Ps (both p < 0.001), with both EM and MA showing less prolate corneal shapes in older age groups. Partial correlation analyses adjusted for age showed that mean-P and semi-Ps were correlated with multiple refractive-error components (Pearson r = -0.30 to -0.78, all p < 0.05), with higher correlations found along the horizontal semi-Ps in MA (Pearson r = +0.37 to -0.78, all p < 0.01). Compared with EM, MA had more prolate temporal semi-Ps in all the three age groups (p < 0.05). Strikingly, age and refractive errors also had significant impacts on the asymmetry of the corneal shape along the horizontal meridian. CONCLUSIONS: Corneal shapes were influenced by age and MA in the Hong Kong Chinese. These results highlight the importance of controlling these factors when designing a study on corneal shape.
Keywords: Astigmatism
Corneal asphericity
Myopia
Refractive errors
Publisher: Lippincott Williams & Wilkins
Journal: Optometry and vision science 
ISSN: 1040-5488
EISSN: 1538-9235
DOI: 10.1097/OPX.0000000000000073
Rights: Copyright © 2013 American Academy of Optometry
This is a non-final version of an article published in final form in Optometry and Vision Science: November 2013 - Volume 90 - Issue 11 - p 1259-1266. The Optometry and Vision Science's website is available at https://journals.lww.com/optvissci/pages/default.aspx
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