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Title: TWFN : an architectural framework for IoMT-enabled smart healthcare system by functional heart rate variability anomaly detection based on a novel optical fiber sensor
Authors: Wang, Q 
Li, K 
Wang, X 
Wang, X
Qin, J 
Yu, C 
Issue Date: Oct-2025
Source: IEEE transactions on industrial informatics, Oct. 2025, v. 21, no. 10, p. 7891-7901
Abstract: Human vital signs are essential to the healthcare industry and applications of Internet of medical things (IoMT). As a significant vital sign signal, heart rate variability (HRV) provides into the functioning of the human stress levels and overall well-being. However, it is inconvenient for daily long-term HRV monitoring with conventional monitoring methods under the uncomfortable feelings. Moreover, it is hard to detect anomalies in HRV data to provide real-time previews about vital signs. To address these problems, a novel fiber interferometer-based optical fiber sensor is proposed to monitor human vital signs, and we propose a novel deep learning model (TWFN). First, a novel module (ADSN) is proposed to apply graph modeling for obtaining spatial and temporal characteristics of HRV. Subsequently, an unsupervised generative adversarial network (VS-GAN) is proposed for the effective overcoming mode collapse and generator failure to converge to the target distribution better. The outcomes of the experiment might encourage the use of HRV-based healthcare application in IoMT-enabled healthcare sectors.
Keywords: Anomaly detection
Healthcare industry
Heart rate variability (HRV)
Internet of medical things (IoMT)
Optical fiber interferometer
Publisher: Institute of Electrical and Electronics Engineers
Journal: IEEE transactions on industrial informatics 
ISSN: 1551-3203
EISSN: 1941-0050
DOI: 10.1109/TII.2025.3576863
Rights: © 2025 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
The following publication Q. Wang, K. Li, X. Wang, X. Wang, J. Qin and C. Yu, "TWFN: An Architectural Framework for IoMT-Enabled Smart Healthcare System by Functional Heart Rate Variability Anomaly Detection Based on a Novel Optical Fiber Sensor," in IEEE Transactions on Industrial Informatics, vol. 21, no. 10, pp. 7891-7901, Oct. 2025 is available at https://doi.org/10.1109/TII.2025.3576863.
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