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Title: Home-based acupressure for managing constipation and subjective well-being in spinal cord injury survivors : a randomized controlled trial
Authors: Li, MQ 
Li, Y 
Lam, W 
Yeung, WF 
Ho, YS 
Li, JY 
Sun, TC 
Yuen, S
Hu, YL 
Yorke, J 
Issue Date: Nov-2025
Source: Journal of integrative medicine, Nov. 2025, v. 23, no. 6, p. 660-669
Abstract: Background: Spinal cord injury (SCI) survivors often experience constipation, which contributes to a reduced sense of well-being and a lower quality of life. Acupressure offers a non-pharmacological and non-invasive alternative therapy for treating constipation.
Objective: This study examined the effects of home-based acupressure on constipation and subjective well-being among SCI survivors.
Design, setting, participants and interventions: This randomized controlled trial randomly assigned 80 adults from Hong Kong with SCI to two study groups. Using a video demonstration filmed by a registered traditional Chinese medicine practitioner, the intervention group performed home-based acupressure (self-administered or caregiver-assisted) twice daily, 15 min/session, for 10 consecutive days. The control group performed manual light touching of the abdomen with the same frequency and duration as the intervention group. Both groups received defecation education through a structured booklet.
Main outcomes measures: The primary outcome was constipation severity. Secondary outcomes included bowel habits, psychological well-being, and quality of life. Focus group interviews were conducted after the intervention to collect subjective feedback from participants.
Results: Significant group-by-time interaction effects on constipation severity (P = 0.005) and quality of life (P = 0.001) revealed that home-based acupressure produced better results than the control. These treatment effects persisted at the one-month follow-up and continued to have a large effect size (Cohen’s d > 0.8). Compared to the control group, the acupressure group also had improvements in anxiety (Cohen’s d = 0.69) and depression (Cohen’s d = 0.72) at the end of the intervention period. Three qualitative categories were identified from the focus group interviews: improvements in bowel function and management; reduced psychological distress following relief from constipation; and acceptability of home-based acupressure.
Conclusions: Acupressure effectively relieves constipation, enhances psychological well-being, and improves quality of life in people with SCI. These data provide novel evidence supporting the use of home-based acupressure as an acceptable and effective therapy for treating constipation after SCI.
Keywords: Acupressure
Constipation
Psychological health
Quality of life
Spinal cord injury
Subjective well-being
Publisher: Science Press
Journal: Journal of integrative medicine 
ISSN: 2095-4964
EISSN: 2773-0727
DOI: 10.1016/j.joim.2025.08.001
Rights: © 2025 Shanghai Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
The following publication Li, M.-q., Li, Y., Lam, W., Yeung, W. F., Ho, Y. S., Li, J.-y., Sun, T. C., Yuen, S., Hu, Y.-l., & Yorke, J. (2025). Home-based acupressure for managing constipation and subjective well-being in spinal cord injury survivors: A randomized controlled trial. Journal of Integrative Medicine, 23(6), 660-669 is available at https://doi.org/10.1016/j.joim.2025.08.001.
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