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Title: Effects of low-fat food on gallbladder contraction and sonographic image quality
Authors: Yip, JHY 
Wong, KS 
Leung, MWY 
Lee, HK 
Au-Yeung, TL 
Yip, CW 
Hui, J 
Liu, KH
Chiyanika, C 
Issue Date: Nov-2025
Source: Journal of diagnostic medical sonography, Nov./Dec. 2025, v. 41, no. 6, p. 575-582
Abstract: Objective: The aim of this study was to examine the impact of consuming a navel orange, a low-fat food item, on gallbladder contraction and sonographic image quality.
Materials and Methods: Sixty-six healthy Chinese participants underwent sonographic evaluation of their gallbladder volume (GBV) and anterior wall thickness (AWT) after fasting for at least 6 hours. This protocol was repeated 120 minutes after consuming a navel orange. An experienced sonographer rated the quality of the gallbladder images on a five-point Likert scale.
Results: There was no significant change in GBV (14.15 cm³ preprandial vs 14.00 cm³ postprandial, p=.073), AWT (0.154 cm vs 0.157 cm, p=.101), or image quality (both rated 5, p=1.000) after orange intake. GBV correlated with body mass index (p < .05). Among various age groups, no significant differences were noted, across the measured parameters, for both preprandial and postprandial states (p > .05).
Conclusion: In this cohort of participants, navel oranges served as an alternative to fasting for gallbladder sonographic preparation and did not affect image quality.
Keywords: Anterior gallbladder wall thickness
Fasting
Gallbladder volume
Image quality
Low-fat food
Ultrasound
Publisher: Sage Publications, Inc.
Journal: Journal of diagnostic medical sonography 
ISSN: 8756-4793
EISSN: 1552-5430
DOI: 10.1177/87564793251320918
Rights: This is the accepted version of the publication Yip JH-Y, Wong KS, Leung MW-Y, et al. Effects of Low-Fat Food on Gallbladder Contraction and Sonographic Image Quality. Journal of Diagnostic Medical Sonography. 2025;41(6):575-582. Copyright © 2025 The Author(s). DOI: 10.1177/87564793251320918.
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