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Title: Microfluidic biosensors for rapid detection of foodborne pathogenic bacteria : recent advances and future perspectives
Authors: Zhang, J
Ma, C 
Du, Y 
Huang, J
Xue, L
Issue Date: 2025
Source: Frontiers in chemistry, 2025, v. 13, 1536928
Abstract: Rapid detection of foodborne pathogenic bacteria is critical for ensuring food safety and preventing foodborne disease outbreaks. Traditional detection methods, while accurate, are often time-consuming and labor-intensive, making rapid detection technologies a pressing need. Microfluidic biosensors have emerged as a powerful solution, offering high sensitivity, specificity, and rapid analysis with minimal sample volume. In this review, we summarize recent advances in microfluidic biosensor technology, highlighting innovations in detection techniques such as electrochemical and optical microfluidic biosensors. We have also introduced microfluidic components, which are crucial for the implementation of microfluidic biosensors. Based on the current state of this technology development, we finally provide several most important recommendations for future research directions in this emerging research area, which may enable widespread commercialization and adoption in the food industry.
Keywords: Food safety
Foodborne pathogens
Lab-on-chip
Microfluidic biosensors
Rapid analysis
Publisher: Frontiers Research Foundation
Journal: Frontiers in chemistry 
EISSN: 2296-2646
DOI: 10.3389/fchem.2025.1536928
Rights: © 2025 Zhang, Ma, Du, Huang and Xue. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
The following publication Zhang J, Ma C, Du Y, Huang J and Xue L (2025) Microfluidic biosensors for rapid detection of foodborne pathogenic bacteria: recent advances and future perspectives. Front. Chem. 13:1536928 is available at https://doi.org/10.3389/fchem.2025.1536928.
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