Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/10573
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Applied Biology and Chemical Technology | - |
dc.creator | Yan, JK | - |
dc.creator | Wang, WQ | - |
dc.creator | Ma, HL | - |
dc.creator | Wu, JY | - |
dc.date.accessioned | 2015-06-23T09:10:30Z | - |
dc.date.available | 2015-06-23T09:10:30Z | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | http://hdl.handle.net/10397/10573 | - |
dc.language.iso | en | en_US |
dc.publisher | Mdpi Ag | en_US |
dc.rights | © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). | en_US |
dc.rights | The following publication Yan, J. K., Wang, W. Q., Ma, H. L., & Wu, J. Y. (2013). Sulfation and enhanced antioxidant capacity of an exopolysaccharide produced by the medicinal fungus Cordyceps sinensis. Molecules, 18(1), (Suppl. ), 167-177 is available athttps://dx.doi.org/10.3390/molecules18010167 | en_US |
dc.subject | Antioxidant activity | en_US |
dc.subject | Cordyceps sinensis | en_US |
dc.subject | Exopolysaccharide | en_US |
dc.subject | Molecular weight | en_US |
dc.subject | Sulfation | en_US |
dc.title | Sulfation and enhanced antioxidant capacity of an exopolysaccharide produced by the medicinal fungus Cordyceps sinensis | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 167 | - |
dc.identifier.epage | 177 | - |
dc.identifier.volume | 18 | - |
dc.identifier.issue | 1 | - |
dc.identifier.doi | 10.3390/molecules18010167 | - |
dcterms.abstract | EPS-1 was an exopolysaccharide produced by the medicinal fungus Cordyceps sinensis (Cs-HK1). In the present study, EPS-1 was sulfated with chlorosulfonic acid (CSA)-pyridine (Pyr) at different volume ratios, yielding four sulfated derivatives, SEPS-1A, B, C and D, with different degrees of substitution (DS: 0.25-1.38) and molecular weights (17.1-4.1 kDa). The sulfation of EPS-1 occurred most frequently at the C-6 hydroxyl groups due to their higher reactivity. In aqueous solution, the native EPS-1 formed random coils or aggregated networks, but the sulfated derivatives formed single helices. The antioxidant activities of the sulfated EPS-1 derivatives for scavenging hydroxyl radicals (·OH) and 2,2-Azinobis-3-ehtylbenzothiazolin-6-sulfonic acid radicals (ABTS·+) were significantly increased with increasing DS and decreasing molecular weight (MW). Sulfation has thus been shown to be an effective and favorable strategy for improving the physico-chemical properties and bioactivities of fungal polysaccharides. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Molecules, Jan. 2013, v. 18, no. 1, p. 167-177 | - |
dcterms.isPartOf | Molecules | - |
dcterms.issued | 2013 | - |
dc.identifier.isi | WOS:000314032900012 | - |
dc.identifier.scopus | 2-s2.0-84872875547 | - |
dc.identifier.rosgroupid | r67278 | - |
dc.description.ros | 2012-2013 > Academic research: refereed > Publication in refereed journal | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
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Yan_Sulfation_Enhanced_Antioxidant.pdf | 215.04 kB | Adobe PDF | View/Open |
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