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http://hdl.handle.net/10397/105736
Title: | Near-Infrared and visible dual-emitting peptide by modular assembly of nitrobenzoxadiazole and neodymium complexes | Authors: | Yeung, YH Chau, HF Kai, HY Zhou, W Chan, KHY Thor, W Charbonnière, LJ Zhang, F Fan, Y Wu, Y Wong, KL |
Issue Date: | 22-Mar-2024 | Source: | Advanced optical materials, 22 Mar. 2024, v. 12, no. 9, 2302070 | Abstract: | The synthetic difficulty of target-specific lanthanide complexes, despite their unique characteristics, limits their use in in vitro/ in vivo studies and biomedical applications. With commercially available and affordable reagents, a facile synthetic approach is developed to modularly deploy nitrobenzoxadiazole and neodymium complexes onto bioactive peptides. The yielded probes show observable neodymium emission with specific localization to corresponding biotargets in vitro, which became the first example of a stable, water-soluble, and target-specific neodymium(III) complex applicable for in vitro imaging with detectable brightness. | Keywords: | Lanthanide probes Neodymium NIR probes Nitrobenzoxadiazole Solid-phase peptide synthesis |
Publisher: | Wiley-VCH | Journal: | Advanced optical materials | EISSN: | 2195-1071 | DOI: | 10.1002/adom.202302070 | Rights: | © 2024 The Authors. Advanced Optical Materials published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. The following publication Y.-H. Yeung, H.-F. Chau, H.-Y. Kai, W. Zhou, K. H.-Y. Chan, W. Thor, L. J. Charbonnière, F. Zhang, Y. Fan, Y. Wu, K.-L. Wong, Near-Infrared and Visible Dual-Emitting Peptide by Modular Assembly of Nitrobenzoxadiazole and Neodymium Complexes. Adv. Optical Mater. 2024, 12, 2302070 is available at https://doi.org/10.1002/adom.202302070. |
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Yeung_Near‐Infrared_Visible_Dual‐Emitting.pdf | 1.28 MB | Adobe PDF | View/Open |
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