Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/97802
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dc.contributorDepartment of Applied Biology and Chemical Technology-
dc.creatorLaw, GL-
dc.creatorDai, L-
dc.date.accessioned2023-03-23T03:32:57Z-
dc.date.available2023-03-23T03:32:57Z-
dc.identifier.urihttp://hdl.handle.net/10397/97802-
dc.language.isoenen_US
dc.rightsAssignee: The Hong Kong Polytechnic Universityen_US
dc.titleChiral cyclen compounds and their usesen_US
dc.typePatenten_US
dc.description.otherinformationUS11357873; US11357873 B2; US11357873B2; US11,357,873; US11,357,873 B2; 11357873; Appl. No. 16/334464en_US
dcterms.abstractThe present invention relates to the preparation of a series of chiral DOTA, DO3A, DO2A, DO1A, cyclen and their metal complexes, which display properties superior to those of previous DOTA-based compounds, and hence are potentially valuable as a platform for diagnostic applications. The chiral DOTAs reveal a high abundance of twisted square antiprism (TSA) geometry favoring them to be used as potential MRI contrast agents, whereas their rapid labelling properties at mild conditions make them excellent candidates for use as radiometal chelators.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationUS Patent US11,357,873 B2. Washington, DC: US Patent and Trademark Office, 2022.-
dcterms.issued2022-06-14-
dc.description.countryUS-
dc.description.validate202303 bcch-
dc.description.oaVersion of Recorden_US
dc.description.pubStatusPublisheden_US
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