Bionic water response shape memory polyamino acid material and preparation method thereof

Abstract

The invention provides a bionic water response shape memory polyamino acid material, which comprises a block A with a beta-folding structure and a hydrophilic block B. The block A and the block B areconnected, wherein the block A is at least one of poly-L-alanine, poly-L-glycine, L-alanine and L-glycine copolymer, the block B is at least one of polyamino acids with an alpha-spiral structure and/or at least one of hydrophilic pyridine derivatives, and the polyamino acid is selected from polyglutamate, polyleucine, polyvaline and polytyrosine. 本发明提供了一种仿生水响应形状记忆聚氨基酸材料，包括具有β‑折叠结构的A嵌段和亲水的B嵌段，且所述A嵌段与所述B嵌段连接，其中，所述A嵌段为聚L‑丙氨酸、聚L‑甘氨酸、L‑丙氨酸和L‑甘氨酸共聚物中的至少一种，所述B嵌段为具有α‑螺旋结构的聚氨基酸中的至少一种和/或亲水性吡啶衍生物中的至少一种，所述聚氨基酸选自聚谷氨酸酯、聚亮氨酸、聚缬氨酸、聚酪氨酸。