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http://hdl.handle.net/10397/5793
| Title: | Water-soluble polymer-based cantharimides as potentially selective anti-tumor agents | Authors: | Tang, JCO Chan, ASC Lam, KH Chui, CH Kok, SHL Yuen, CWM Chan, SH Cheng, CH Cheung, F |
Issue Date: | 1-Jan-2013 | Source: | US Patent 8,344,007 B2. Washington, DC: US Patent and Trademark Office, 2013. | Abstract: | A cantharimide compound may include the backbone of formula (1). R¹, R², R³, and R⁴ may be independently selected from the group consisting of H, C(O)OR⁵, C(O)R⁶, C(O)NR⁷R⁸, NR⁹C(O)R¹⁰, N--R¹¹R¹², O--R¹³, S--R¹⁴, P(O)(OR¹⁵)(OR¹⁶), As(O)(OR¹⁷)(OR¹⁸), SO₂R¹⁹, SO₃R²⁰, and B(OR²¹). X¹ to X⁴ may be independently selected from the group consisting of nitrogen and carbon, such that X¹ to X⁴ are not all hydrogen. Y¹, Y² and R⁵ to R²¹ may be independently selected from the group consisting of hydrogen, C₁₋₁₂-alkyl, -aryl, heteroaryl, and a bioactive polymer. | Rights: | Assignee: The Hong Kong Polytechnic University. |
| Appears in Collections: | Patent |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| us8344007b2.pdf | 1.05 MB | Adobe PDF | View/Open |
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