Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/4590
| Title: | Method of biosynthesizing tetrodotoxin | Authors: | Yu, PH Yu, CF |
Issue Date: | 12-Jul-2011 | Source: | US Patent 7,977,074 B2. Washington, DC: US Patent and Trademark Office, 2011. | Abstract: | The present invention relates methods for the biosynthesis of tetrodotoxin (TTX) involving the steps of obtaining a culture possessing one or more of a Vibrio species, such as through a seed culture, inoculating the culture and tissue extract from a textrodotoxin-bearing organism in a fermenter medium, and isolating and purifying tetrodotoxin from said fermenter, resulting in a yield of TTX of about 0.5 g TTX/L in about 3 to 5 days, such TTX being at least 90% pure. | Rights: | Assignee: The Hong Kong Polytechnic University. |
| Appears in Collections: | Patent |
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| us7977074b2.pdf | 304.04 kB | Adobe PDF | View/Open |
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