Methods and agents of decalcifying bone

Abstract

Decalcification can be performed by using acid or other agents. It may be difficult to decalcify large bone block within ours. This invention provides a bone-decalcifying agent including a calcium desolving agent for desolving calcium ions of bones, and a bubble-forming agent for generating microbubbles when the bone-decalcifying agent is exposed to ultrasonic vibration. It is found that bones may be decalcified in a relatively short time using the bone-decalcifying agent of this invention. 脱钙可通过使用酸或其它试剂来进行。现有的方法可能对大骨块脱钙有困难。本发明提供了一种包含溶解骨钙离子的钙溶剂和一种当骨脱钙剂受到超声波振动时产生微泡的起泡剂。已发现，使用本发明的骨脱钙剂可使骨以相对短的时间被脱钙。