Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/4600
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Title: Spectropolarimetric imaging for pathological analysis of skin
Authors: Zhao, Y
Zhang, L 
Pan, Q
Issue Date: 1-Apr-2009
Source: Applied optics, 1 Apr. 2009, v. 48, no. 10, p. D236-D246
Abstract: Pathological changes of skin will change the tissue's birefringence and structure, which can be measured by the polarization and spectral changes of the tissue's scattering light. Light-scattering spectropolarimetry is an effective tool to measure these features for quantitative pathology analysis. An epithelial tissue imaging spectropolarimeter is proposed to acquire the spectral, polarimetric, and spatial characteristic changes of the tissue, and then a spectropolarimetric correction method is proposed to compute the tissue's polarimetric spectrum, which can be used for pathological analysis of tissue. Finally, to aid doctors for more accurate clinical diagnosis, a false color mapping based spectropolarimetric image fusion method is proposed to enhance the visual differences between normal skin and pathological skin. Experimental results demonstrate the potential of the proposed techniques for pathological diagnosis and treatment evaluation of skin.
Keywords: Diagnosis
Image fusion
Light scattering
Polarimeters
Polarographic analysis
Skin
Publisher: Optical Society of America
Journal: Applied optics 
ISSN: 1559-128X
EISSN: 2155-3165
DOI: 10.1364/AO.48.00D236
Rights: © 2009 Optical Society of America. This paper was published in Applied Optics and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-48-10-D236. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
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