Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/4590
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Title: Method of biosynthesizing tetrodotoxin
Authors: Yu, PH
Yu, CF
Issue Date: 12-Jul-2011
Source: US Patent 7,977,074 B2. Washington, DC: US Patent and Trademark Office, 2011.
Abstract: The present invention relates methods for the biosynthesis of tetrodotoxin (TTX) involving the steps of obtaining a culture possessing one or more of a Vibrio species, such as through a seed culture, inoculating the culture and tissue extract from a textrodotoxin-bearing organism in a fermenter medium, and isolating and purifying tetrodotoxin from said fermenter, resulting in a yield of TTX of about 0.5 g TTX/L in about 3 to 5 days, such TTX being at least 90% pure.
Rights: Assignee: The Hong Kong Polytechnic University.
Appears in Collections:Patent

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