Phosphine ligand of benzimidazole-indole skeleton, preparation method and application of phosphine ligand

Abstract

The invention provides a phosphine ligand of a 2-(3-(disubstituted phosphanyl)-N-alkyl-1H-indole-2-yl)-N-alkyl-benzimidazole skeleton, a preparation method and an application of the phosphine ligand. The structure of the phosphine ligand of the 2-(3-(disubstituted phosphanyl)-N-alkyl-1H-indole-2-yl)-N-alkyl-benzimidazole skeleton is represented as a following formula, wherein the R<1> and R<2> are separately ones selected from a group consisting of hydro, alkyls of C1-10, alkoxy, oxyalkyl, phenyl and pyridyl, the R<3> is selected from phenyl or alkyl, and the R<4> and the R<5> are separately ones selected from a group consisting of hydro, alkyls, alkoxy, oxyalkyl, phenyl, fluoro and chloro. 本发明提供了一种2‑(3‑(二取代膦基)‑N‑烷基‑1H‑吲哚‑2‑基)‑N‑烷基‑苯并咪唑骨架的膦配体及其制备方法和应用。所述2‑(3‑(二取代膦基)‑N‑烷基‑1H‑吲哚‑2‑基)‑N‑烷基‑苯并咪唑骨架的膦配体，其结构如下式所示：其中，所述R1、R2单独为氢基、C1-10的烷基、烷氧基、氧烷基、苯基、吡啶基中的一种，所述R3为苯基或者烷基，所述R4、R5单独为氢基、烷基、烷氧基、氧烷基、苯基、氟基、氯基中的一种。