Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/8717
Title: Acute post-ingestion changes in plasma ascorbic acid concentration : relationship to dose and to existing body stores
Authors: Benzie, IFF 
Strain, JJ
Keywords: Antioxidants
Ascorbic acid
Dose-Response
Human
Supplements
Vitamin C
Issue Date: 1997
Source: Nutrition research, 1997, v. 17, no. 2, p. 187-190 How to cite?
Journal: Nutrition Research 
Abstract: Plasma ascorbic acid concentrations were measured in 27 adults before and after ingestion of 0.5 - 3.0 g of vitamin C. Mean (SEM) fasting concentration was 64 (3) μmol/l, with no significant male-female difference. There was a significant correlation between the response and log dose (r = 0.928; P <0.01). There was no significant correlation (r = 0.14; P >0.1) between the dose-corrected increase and the fasting concentration; 0.5 g caused a greater increase than 0.25 g (mean increases 56 and 33 μmol/l respectively; P <0.01); doses of 1.0 g and 2.0 g did not cause significantly greater responses. Results indicate that i) response to ingestion of vitamin C is close dependent and independent of body stores of the vitamin, ii) a 0.5g dose appears optimal in terms of increasing the plasma ascorbic acid concentration.
URI: http://hdl.handle.net/10397/8717
ISSN: 0271-5317
DOI: 10.1016/S0271-5317(96)00250-3
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