Please use this identifier to cite or link to this item:
Title: Altered connectivity of the visual word form area in the low-vision population : a resting-state fMRI study
Authors: Zhou, W
Pang, W
Zhang, L
Xu, H
Li, P 
Shu, H
Issue Date: Feb-2020
Source: Neuropsychologia, Feb 2020, v. 137, 107302
Abstract: The present study investigated the resting-state functional connectivity (FC) of the visual word form area (VWFA) in low-vision people. Participants were 25 sighted and 37 low-vision individuals. During the experiment, participants underwent resting-state functional magnetic resonance imaging (rs-fMRI) scans. FC maps of the VWFA for sighted and low-vision participants were calculated separately and were contrasted with each other. Our results revealed a stronger FC between the VWFA and the inferior occipital cortex (IOC) but a weaker FC between the VWFA and the posterior central gyrus (PostCG) in the sighted people compared to the people with low vision. The region-of-interest-based analyses showed that the FC between the VWFA and PostCG in low-vision individuals who learned Braille was stronger relative to those who did not learn Braille, and that the FC between the VWFA and IOC was correlated with the onset age of Braille learning. These results suggest that the VWFA in people with low vision has a functional reorganization between visual and tactile processing, which was modulated by the experience of Braille reading.
Keywords: Functional connectivity
Low vision
Resting state
Visual word form area
Publisher: Pergamon Press
Journal: Neuropsychologia 
ISSN: 0028-3932
EISSN: 1873-3514
DOI: 10.1016/j.neuropsychologia.2019.107302
Appears in Collections:Journal/Magazine Article

View full-text via PolyU eLinks SFX Query
Show full item record

Page view(s)

Citations as of Jul 7, 2020

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.